The kSort® Assay by Immucor
kSORT is a non-invasive gene expression assay that enables enhanced post-transplant surveillance and monitors immune quiescence for transplant patients.
Join the (R)Evolution of non-invasive post transplant surveillance by using the latest gene expression assay to rule out sub clinical or clinical rejection.
ATC 2021 Virtual Connect
June 4-9, 2021
The Need for a Non-Invasive Alternative to Surveillance Biopsies
Fewer Costly Procedures
Less invasive methods are likely to reduce costs
Avoid Procedure Related Risks
Procedure-related adverse events including graft bleeding (up to 6% across indications) or arteriovenous fistula (up to 14%)
Reduce Sampling Error
~20% clinical discordance with inter-observer variance
A Comprehensive Portfolio for the Continuum of Transplant Patient Care
For more than 30 years, Immucor has focused on improving patient outcomes by bringing together best-in-class solutions developed to meet specific clinical needs. In addition to offering market-leading assays for typing and screening blood used in lifesaving transfusions, we offer a comprehensive—and progressively expanding—portfolio of products, technologies, and services to support transplant teams across the entire continuum of transplant patient care.
kSort Collection Time Points
kSORT can be utilized to monitor patient immune responses to kidney transplantation throughout the transplant journey and can add another perspective to better monitor and prevent graft damage or loss. A suggested protocol driven collection time scenario is presented here to illustrate how kSORT could be used to monitor kidney transplant patients over time.
Test 1x / month
Test every 2 months
Test every 6 months
How to Order kSort
Immucor DX strives to provide excellent customer service, starting with streamlining the logistics of ordering the kSORT test.
Complete test requisition and collect whole blood specimen
Complete requisition form and draw specimen in provided PAXgene® tubes according to included instructions. Click here for electronic copies of the test requisition and instructions.
Package specimen and contact carrier for pickup
Package the specimen and test requisition in accordance with the provided instructions, apply the pre-paid return shipping label, and call carrier for pickup.
Receive results in < 1 week
Physician receives report within 72 hours of specimen receipt at Immucor DX.
Immune Regulation Pathways
The kSORT assay evaluates the change in expression of specific genes which are associated with pathways involved with immune activation or stress responses. kSORT gene expression panel has been shown to be valuable in establishing which patients are likely to maintain graft tolerance. The kSORT assay gives health care providers and patients another tool to confirm treatment successes or treatment needs in a complex transplant environment.
kSort Data Studies
kSORT has been evaluated in multiple studies and demonstrates Negative Predictive Value. In conjunction with standard assessments, kSORT can aid physicians in compiling relevant information to avoid unnecessary biopsies and better predict rejection in kidney transplant patients.
|AART 100 1||93%||View Study|
|PRISM 2||92%||View Study|
|SAILOR 3||98%||View Study|
|ESCAPE 4||90%||View Study|
|Van Loon Study 5||90%||View Study|
- 1 Roedder S., Sigdel T., Salomonis N., Sarwai M., et al. PLoS Med. 11, (2014)
- 2 Vincenti F., et al. Abstract, American Transplant Congress (2018)
- 3 Ekberg J, Lindner P et al., Am J Transpl. 16, 203–404 (2016)
- 4 Crespo E., Roedder S., et al. Transplantation 101, 1400–1409 (2017)
- 5 Van Loon E., et al. Am. J Transpl. 00, 1-11 (2020)
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Speak with a Specialist
Do you want to learn more? Our Medical Specialists are available to talk with you today! Use this form to send us an email or call 616-284-3827 if you are ready to order.