LIFECODES ATS-13 Activity Assay is a quantitative assay for the measurement of ADAMTS-13 enzyme activity using FRET technology. A large body of literature shows that ADAMTS-13 is the protease responsible for cleaving von Willebrand Factor. Significant decreases or an absence of ADAMTS-13 activity can lead to the formation of ultra-large vWF fragments. Antibodies against ADAMTS-13 have also been shown to cause a decrease in ADAMTS-13 activity.1
LIFECODES ATS-13 Activity Assay offers the following benefits:
- Easy: Assay set-up in less than 10 minutes
- Fast: Results in under 45 minutes
- Sensitive: Fluorescent endpoint
1 LIFECODES ATS-13 Activity Assay for research use only [package insert], Waukesha, WI; Immucor GTI Diagnostics, Inc., 2013.