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ATS-13® Activity Assay

What is your testing algorithm for patients suspected of having thrombotic thrombocytopenic purpura (TTP)?

ATS-13 Activity Assay provides protocols to quantitatively measure ADAMTS-13 protease activity and determine the presence of inhibitory antibodies to ADAMTS-13 in human plasma.

ADAMTS-13 is the protease that cleaves von Willebrand Factor. Significant decreases or an absence of ADAMTS-13 activity can lead to the formation of ultra-large vWF fragments and trigger intravascular platelet aggregation and microthrombosis, causing the signs and symptoms of thrombotic thrombocytopenic purpura, TTP.

Quick and Easy

  • Set up in less than 10 minutes
  • Pre-diluted calibrators
  • Results in under 45 minutes

Sensitive

  • Utilizes fluorescence resonance energy transfer (FRET) technology with less test variability
  • % Activity and % Inhibition derived from a fluorescent endpoint

Research Use Only (RUO). Not for use in diagnostic procedures.

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