ATS-13 Activity Assay provides protocols to quantitatively measure ADAMTS-13 protease activity and determine the presence of inhibitory antibodies to ADAMTS-13 in human plasma.
ADAMTS-13 is the protease that cleaves von Willebrand Factor. Significant decreases or an absence of ADAMTS-13 activity can lead to the formation of ultra-large vWF fragments and trigger intravascular platelet aggregation and microthrombosis, causing the signs and symptoms of thrombotic thrombocytopenic purpura, TTP.
Quick and Easy
- Set up in less than 10 minutes
- Pre-diluted calibrators
- Results in under 45 minutes
- Utilises fluorescence resonance energy transfer (FRET) technology with less test variability
- % Activity and % Inhibition derived from a fluorescent endpoint
Research Use Only (RUO). Not for use in diagnostic procedures.