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ATS-13^® Activity Assay

What is your testing algorithm for patients suspected of having thrombotic thrombocytopenic purpura (TTP)?

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ATS-13 Activity Assay provides protocols to quantitatively measure ADAMTS-13 protease activity and determine the presence of inhibitory antibodies to ADAMTS-13 in human plasma.

ADAMTS-13 is the protease that cleaves von Willebrand Factor. Significant decreases or an absence of ADAMTS-13 activity can lead to the formation of ultra-large vWF fragments and trigger intravascular platelet aggregation and microthrombosis, causing the signs and symptoms of thrombotic thrombocytopenic purpura, TTP.

Quick and Easy

Set up in less than 10 minutes
Pre-diluted calibrators
Results in under 45 minutes

Sensitive

Utilises fluorescence resonance energy transfer (FRET) technology with less test variability
% Activity and % Inhibition derived from a fluorescent endpoint

Research Use Only (RUO). Not for use in diagnostic procedures.